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Size:60 CT Jarrow Formulas pharmaceutical grade, stabilized SAM-e JOINT provides a full 200 mg SAM-e (net yield) and 525 mg of glucosamine hydrochloride in every enteric-coated tablet. SAM-e JOINT is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product. SAM-e and glucosamine are known to benefit joint function and recuperation. Contains More of the Active S;S Form. Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow FORMULAS SAM-e is made naturally by microbiological fermentation and then specially processed without solvents to preserve 68-80% (S,S) SAM-e, the highest active level available. Glucosamine is an aminosaccharide synthesized by transamidase enzymes from glucose and an amine group from glutamine. HCl (hydrochloric acid) stabilizes the glucosamine in this product. Glucosamine is a component of joint and intestinal tissue and is involved in the production of synovial fluid that lubricates the joints. SAM-e has been clinically shown to have the following benefits: Joint Strength, Brain Metabolism, Longevity and Liver Function.